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Aspect Results of Trazodone to Be Conscious of — Talkspace

Printed on: 23 Could 2023

Side Effects of Trazodone to Be Aware of

Trazodone is an antidepressant remedy that’s sometimes prescribed to deal with depressive dysfunction and nervousness dysfunction and is used off-label for insomnia sleep problem. Trazodone works by altering serotonin ranges within the mind to enhance temper and sleep high quality. Whereas Tradozone use may be useful, there are widespread unwanted effects and dangers to grasp and take into account like with each remedy.

Figuring out the unwanted effects of Trazodone drugs is essential for those who’re contemplating taking this drug to alter your serotonin ranges — maintain studying to be taught extra. We’re masking every widespread facet impact, extreme however uncommon results to concentrate on, and find out how to handle any hostile results you would possibly expertise after you begin taking this drug.   

Frequent Aspect Results of Trazodone

Probably the most outstanding Trazodone facet impact is drowsiness. In truth, the drug is commonly used off-label to deal with insomnia. Different widespread unwanted effects of Trazodone can embrace:

  • Nausea
  • Vomiting
  • Dry mouth 
  • Throat irritation
  • Headache
  • Stomach ache
  • Constipation
  • Low blood stress
  • Itchy eyes
  • Disorientation
  • Blurred imaginative and prescient
  • Coordination points
  • Fainting

Much less Frequent Aspect Results of Trazodone

Weight achieve 

Does Trazodone trigger weight achieve? Gaining weight is never skilled when taking Trazodone drugs. Scientific trials recommended that simply 1% of individuals would possibly achieve weight after taking it. Nevertheless, some later analysis exhibits each weight achieve and loss are doable. 


Incontinence is one other uncommon facet impact of excessive doses of Trazodone. Analysis suggests that individuals with urinary incontinence ought to critically take into account this and maybe seek the advice of with a healthcare supplier earlier than taking Trazodone. 

Sexual dysfunction

In response to research, an estimated 1.5% of individuals taking Trazodone can have decreased intercourse want because of the drug. Most individuals see a return of sexual want and genital sensitivity in time, although. 

Psychiatry and Prescriptions On-line

Obtain an analysis and prescription for psychological well being remedy (if wanted) from a psychiatry-trained medical supplier.

Critical Aspect Results of Trazodone

Critical unwanted effects from taking Trazodone embrace suicidal ideas, worsening signs of despair, and decreased immune system effectivity. 

“There are a few unwanted effects of Trazodone that we have to watch. The primary one is an irregular coronary heart rhythm, too quick or too gradual. It may possibly additionally lower the immune system’s effectivity, resulting in extra colds and infections. Bowel motion and urination irregularities may also be trigger for concern. Unexplained bruising, complications, aches and pains, confusion, nervousness, fainting, coordination points, and blurred imaginative and prescient that choose up in frequency ought to be monitored.”

Talkspace therapist Meaghan Rice, PsyD, LPC

Different reactions can happen because of Trazodone use, together with: 

  • Seizures 
  • Probability in coronary heart fee (quickening or slowing irregular heartbeat)
  • Adjustments in habits, comparable to aggression or agitation
  • Hallucinations
  • Problem respiration

When you see any of those indicators affecting psychological well being comparable to suicidal ideas whereas on Trazodone, contact your physician instantly.  

Do Trazodone Aspect Results Go Away?

The excellent news is that the majority of Trazodone’s unwanted effects will resolve as your physique adjusts to having the drug in your system. Nevertheless, if any widespread facet impact persists or worsens, it is best to ask your physician or healthcare supplier about altering your dosage or switching medicines altogether.

How lengthy do Trazodone unwanted effects final?

Whereas most individuals discover hostile unwanted effects start to subside in time, some could expertise them for prolonged durations and wish to discuss to their physician. 

Learn how to Handle Trazodone Aspect Results

When you’re experiencing any disagreeable unwanted effects associated to Trazodone, your physician may give you concepts on how one can handle every hostile facet impact. 

For instance, easy methods to fight Trazodone unwanted effects embrace:

  • Monitoring your signs
  • Adjusting dosage quantity
  • Altering the time of day you are taking it, or whether or not you are taking it with meals or with out 
  • Making life-style modifications comparable to yoga, meditation, and exercising recurrently  
  • Hydrating
  • Utilizing pure treatments like consuming ginger tea for nausea or taking probiotics for intestine well being

“Managing Trazodone unwanted effects may embrace consuming extra water, supporting a wholesome life-style, eliminating drug use — particularly NSAIDS and cigarette smoking — limiting or eliminating caffeine and/or alcohol, telling your physician something and every thing you’re already taking, being cautious about dangerous actions that don’t permit room for the sedative impact of Trazodone, and ensuring your physician is aware of every thing about earlier medical situations.”

Talkspace therapist Meaghan Rice, PsyD, LPC

See If Trazodone Is Proper for You with Talkspace Psychiatry

Trazodone unwanted effects can vary from delicate to extreme, and it’s vital for anybody contemplating this remedy to concentrate on them. Although most unwanted effects are non permanent, realizing that they might nonetheless happen is important. That is particularly vital for those who’re contemplating stopping remedy as there’s a likelihood of experiencing Trazodone withdrawal signs. 

When you’re trying into whether or not Trazodone could also be a great match in your psychological well being wants, Talkspace on-line psychiatry companies provide personalised assessments with licensed professionals who may also help decide if this or some other remedy may gain advantage you. Get assist  at present.


  1. DailyMed – Trazodone Hydrochloride Pill. U.S. Nationwide Library of Medication. Accessed March 10, 2023. 
  2. Gica S. Investigation of the impact of Trazodone on spontaneous and acetylcholine-induced bladder detrusor easy muscle contractions. Dusunen Adam:The Journal of Psychiatry and Neurological Sciences. 2022. doi:10.14744/dajpns.2022.00170.  Accessed March 10, 2023. 
  3. Trazodone hydrochloride – Drug Abstract. Trazodone Hydrochloride (trazodone hydrochloride) dose, indications, hostile results, interactions… from PDR.internet. https://www.pdr.internet/drug-summary/Trazodone-Hydrochloride-trazodone-hydrochloride-3033.1692. Accessed March 10, 2023. 

Talkspace articles are written by skilled psychological health-wellness contributors; they’re grounded in scientific analysis and evidence-based practices. Articles are extensively reviewed by our staff of scientific specialists (therapists and psychiatrists of assorted specialties) to make sure content material is correct and on par with present trade requirements.

Our objective at Talkspace is to supply essentially the most up-to-date, helpful, and goal data on psychological health-related subjects as a way to assist readers make knowledgeable choices.

Articles comprise trusted third-party sources which are both immediately linked to within the textual content or listed on the backside to take readers on to the supply.

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